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| Year : 1996 | Volume
: 1
| Issue : 2 | Page : 79-82 |
Pre and postoperative cortisal secretion in neonates undergoing surgery for esophageal atresia.
V Bhatnagar, MG. Karmakar
All Institute of Medical Sciences, New Delhi-110029, India
Correspondence Address:
V Bhatnagar
All Institute of Medical Sciences, New Delhi-110029
India
 Source of Support: None, Conflict of Interest: None  | Check |
ABSTRACT: Pre-and postoperative cortisol levels were measured in clotted blood of 27 neonates who underwent surgery for esophageal atresia with or without tracheo-esophageal fistula. The pre-operative and 6 hours postoperative values were 40.6 plus minues 29.0 and 41.5 plus minues 33.0 meug/dl respectively (p-value-not significant). These values were further analyzed with regard to various clinical and biochemical parameters. The results indicated that factors which did not significantly affect the postoperative cortisol response included age, color, temperature, weight, pneumonitis, respiratory distress, hemoglobin, blood sugar, duration of surgery, sedation, anaesthetic complications, starvation and ventilatory support. The changes with regard to blood transfusion requirements were almost significant (p less than 0.06) while the amount of blood loss was directly proportional to increase in the cortisol response (p less than 0.02).
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