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| Year : 1997 | Volume
: 2
| Issue : 4 | Page : 126-129 |
Topical sucralfate : role in the prevention and healing of skin excoriations around enterostomas, Gastro-intestinal fistulas and perineal region.
S Mantoo, VK Raina
Department of Surgery, Medical College, Jabalpur-482003
Correspondence Address:
S Mantoo
Department of Surgery, Medical College, Jabalpur-482003
 Source of Support: None, Conflict of Interest: None  | Check |
ABSTRACT: Peristomal and perineal excoriations and excoriations around gastro-intestinal fistulas occur commonly despite preventive measures. The continuous chemical irritation leads to cutaneous denudation and chronic discomfort. A multitude of topical agents have been tried. We present our experience using topical sucralfate, a drug commonly used in peptic ulceration. Sixty patients divided into two groups-prevention (n=25) and healing (n=35) were included in the study. Each group was divided into subgroups for comparison of results with topical aluminium paint and siloderm ointment. Sucralfate, prepared either as a powder or an emollient (in glycerol base) was applied liberally for both prevention and healing of skin excoriations. Complete prevention of excoriations was achieved in patients in whom topical sucralfate was applied and more than 90 percent cases had complete healing of excoriations with topical sucralfate. General observations included; (1) A lag time of 2 to 3 days before visible healing was evident; (2) sucralfate was soothing, non-toxic and non-allergic even after long term use; (3) complete re-epithelization occurred in more than 90 percent cases after 110 days of application of sucralfate and (4) sucralfate was cost effective and superior to both aluminium paint and siloderm ointment.
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