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| Year : 1999 | Volume
: 4
| Issue : 4 | Page : 192-195 |
Efficacy of OK-432 in pediatric lymphangiomas-Preliminary experience.
DK Gupta, M Bajpai, M Srinivas, A Lall, S Dave, S Ogita
Department of Pediatric Surgery, All Institute of Medical Sciences, New Delhi, India
Correspondence Address:
DK Gupta
Department of Pediatric Surgery, All Institute of Medical Sciences, New Delhi
India
 Source of Support: None, Conflict of Interest: None  | Check |
ABSTRACT: Aim:Lymphangiomas are characterized by a proliferation of small lymphatics and vessels with intervening fibrous tissue and this is a common condition seen in children. Surgical excision of these leaves behind tell tale signs which could aesthetically be relevant to the child. OK-432 is a promising alternative for this condition. This study was designed to evaluate the effectiveness of OK-432 in the treatment of lymphangiomas in children. Patients and Methods:Twenty-four patients with clinical diagnosis of lymphangioma underwent the treatment, between the period 1996-1998, with OK-432 and formed the study group of this non-randomized clinical trial. Upon investigation 12 were cystic and the remaining were diffuse. Results: Seven out of the 12 cystic lymphangiomas responded very well. The remaining showed a partial response. All the 12 cases of diffuse variety showed poor response. conclusions: Intrta-lesional OK-432 is best suitable for the cystic variety of lymphangioma. this therapy has minimal side effects and should be the first choice for the treatment of cystic lymphangiomas.
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