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Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
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Year : 2004  |  Volume : 9  |  Issue : 1  |  Page : 3-7

Bleomycin as intralesional sclerosant for cystic hygromas

Dept. of Pediatric Surgery, PGIMER, Chandigarh, India

Correspondence Address:
JK Mahajan
Dept. of Pediatric Surgery, PGIMER, Chandigarh
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Source of Support: None, Conflict of Interest: None

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ABSTRACT: To study the efficacy of intralesional bleomycin as a sclerosing agent for peripheral cystic hygromas, 15 patients were treated. Intralesional injection of bleomycin into the lymphangiomas was given at a dose not exceeding 0.5 mg per kg of body weight, at intervals of 2 weeks. The regression response of the swelling was graded as excellent (total disappearance), good ( 50 percent reduction), and poor ( 50 percent decrease). Reduction in the size of the mass was usually seen by 2 weeks to 6 months and the number of injections for each patient varied from 1-5. A significant reduction was seen in 86.7 percent (13 patients) and 53.3 percent (8 cases) of them showed complete disappearance. Eleven of the 12 cystic lesions showed excellent to good response. No significant complications were noted. The average follow-up period was 28 months (23-37 months).


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  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

Online since 1st May '05