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Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
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Year : 2004  |  Volume : 9  |  Issue : 1  |  Page : 8-14

Comparison of caudal bupivacaine and morphine for relief of postoperative pain in children

Dept. of Anesthesiology and Intensive Care, AIIMS, New Delhi, India

Correspondence Address:
MK Arora
Dept. of Anesthesiology and Intensive Care, AIIMS, New Delhi
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Source of Support: None, Conflict of Interest: None

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ABSTRACT: Background and Objectives: The study was aimed to compare the efficacy, duration and side effects of combination of bupivacaine 0.25 percent with low dose morphine 0.03 mg/kg and bupivacaine 0.25 percent alone injected into the caudal space for relief of postoperative pain in children undergoing various procedures. Methods: Eighty children aged between 1-10 years undergoing urogenital, orthopedic and lower abdominal general surgical procedures were studied. In 40 patients (Group I) bupivacaine alone and in another 40 patients (Group II) morphine (0.03 mg/ kg) mixed with bupivacaine was given caudally after induction of anesthesia. Patients were selected for each of these therapies by draw of random numbers. Results: The mean duration of analgesiawas 8.2 plus-minus 2.4 hours (range 5-12 hours) in bupivacaine group and 20.8 plus-minus 3.4 hours (range 12-26 hours) in morphine mixed with bupivacaine group. No serious side effect like respiratory depression or apnea was seen in any patient and there was no significant difference in the incidence of nausea, vomiting and urinary retention between the 2 groups. Conclusions: We conclude that low dose morphine (0.03 mg/kg) combined with 0.25 percent bupivacaine given caudally gave longer duration of analgesia in children undergoing urogenital, general surgical and orthopedic procedures without significant side effects.


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  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

Online since 1st May '05