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Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
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Year : 2004  |  Volume : 9  |  Issue : 2  |  Page : 67-73

Pediatric germ cell tumors : an overview

Dept. of Pathology and Pediatric Surgery Medical College, 88, College Street, Kolkata-700073

Correspondence Address:
S Chattopadhyay
Dept. of Pathology and Pediatric Surgery Medical College, 88, College Street, Kolkata-700073

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Source of Support: None, Conflict of Interest: None

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ABSTRACT: The present series describes the retrospective analysis of 75 pediatric patients diagnosed as germ cell tumors after surgery and histopathology collected over last 20 years. The Male: Female ratio was 23: 52. Age of the patients at presentation ranged from 3 days to 10 years, of which 12 cases presented in neonatal period, 43 cases between 1 month and 3 years, and 13 cases between 4 and 7 years and 7 patients were above 8 years. Extragonadal location was twice commonly involved compared to gonadallocation (50:25). Among extragonadal sites, sacrococcygeal region was the commonest to be involved (41 cases) followed by retroperitoneum (6 cases). Present series recorded only single cases of germ cell tumors each of mediastinum, stomach and vagina. Ovary was the site of involvement in 18 cases and testis in 7 cases. Mature (benign) teratoma was the commonest histopathological diagnosis (58 cases), followed by dysgerminoma (6 cases), yolk sac tumor (5 cases), immature teratoma and embryonal carcinoma (3 cases each). Patients with mature teratoma were treated with surgical excision only and complete removal was curative. Malignant germ cell tumors required radiotherapy and chemotherapy. Follow-up data were recorded.

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  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

Online since 1st May '05