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Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
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Year : 2009  |  Volume : 14  |  Issue : 2  |  Page : 73-75

Embryogenesis of esophageal atresia: Is localized vascular accident a factor?

Department of Pediatric surgery, Assam Medical college, Dibrugarh, Assam, India

Correspondence Address:
Hemonta K Dutta
Assam Medical College & Hospital, Dibrugarh, Assam-786 002
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-9261.55158

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Several theories on embryogenesis of esophageal atresia have been proposed, none could explain the whole spectrum of this anomaly. We report a new variant of esophageal atresia in which the two blind pouches were joined by an atretic band. Histology of the atretic part showed groups of striated muscle arranged haphazardly without any lumen. The existing theories on etiology of esophageal atresia cannot explain this variant. However, localized vascular accident during intrauterine life resulting in disturbances in regional microcirculation could be a possible factor as demonstrated by Louw and Barnard in relation to jejunoileal atresia. This is contrary to the current understanding that disproportionate growth of the horizontal esophageal folds results in esophageal atresia.


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  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

Online since 1st May '05