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CASE REPORT |
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| Year : 2010 | Volume
: 15
| Issue : 3 | Page : 108-109 |
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Pyloric and antral strictures following corrosive acid ingestion: A report of four cases
Ram Mohan Shukla1, Madhumita Mukhopadhyay2, BB Tripathy1, KC Mandal1, B Mukhopadhyay1
1 Department of Pediatric Surgery, N. R. S. Medical College and Hospital, Kolkata 14, India
2 Department of Pathology, IPGMER, Kolkata 20, India
| Date of Web Publication | 18-Oct-2010 |
Correspondence Address:
B Mukhopadhyay
7E, Dinobandhu Mukherjee Lane, Sibpur, Howrah 711 102, West Bengal
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0971-9261.71749
 Abstract | | |
This study reports four children who developed complete stricture of pylorus and antrum of the stomach following accidental ingestion of corrosive agent (toilet cleaner).
Keywords: Acid ingestion, acquired antral stricture, acquired pyloric stricture, gastric outlet obstruction, gastrojejunostomy
How to cite this article:
Shukla RM, Mukhopadhyay M, Tripathy B B, Mandal K C, Mukhopadhyay B. Pyloric and antral strictures following corrosive acid ingestion: A report of four cases. J Indian Assoc Pediatr Surg 2010;15:108-9 |
How to cite this URL:
Shukla RM, Mukhopadhyay M, Tripathy B B, Mandal K C, Mukhopadhyay B. Pyloric and antral strictures following corrosive acid ingestion: A report of four cases. J Indian Assoc Pediatr Surg [serial online] 2010 [cited 2023 Mar 30];15:108-9. Available from: https://www.jiaps.com/text.asp?2010/15/3/108/71749 |
| Introduction | |  |
Ingestion of corrosive agents is not an uncommon cause of benign strictures of the upper aerodigestive tract in India. Easy availability of hydrochloric acid in the form of a cheap toilet cleaner is a frequent cause of pyloric and antral strictures. There are only few reports published highlighting the management of corrosive stricture of pylorus and antrum of the stomach in children. [1] In a study of 220 cases, 52 patients ingested acid agents and 2 of them (3.8%) presented with gastric outlet obstruction without esophageal stricture. [2]
| Case Report | | |
Four children (three boys and one girl), all with a common history of ingestion of toilet cleaner (hydrochloric acid), were admitted in our department and managed successfully. Ages of the patients were 1 year 7 months, 4 years, 5 year 4 months, and 9 years. All of them took it accidentally. Exact amount of acid ingested was not available. The patients were treated conservatively in peripheral hospitals (intravenous fluid, antibiotics, H2 receptor blockers, and steroids) before being referred to us for surgical intervention. Mean duration of conservative treatment was 4 weeks (range from 3 to 6 weeks). Three patients presented with nonbilious vomiting after each feed and only one patient was tolerating small amount of liquid.
The mean body weight before acid ingestion was 15 kg (range, 8-30 kg) and average weight at the time of surgical intervention was 9.25 kg (range, 5-18 kg) with a mean weight loss was 38% (range, 33-40%). All these patients were nutritionally depleted. Clinical examination of abdomen revealed epigastric fullness in two patients. Near complete gastric outlet obstruction was seen in all cases in upper gastrointestinal contrast study. Gastroduodenoscopy revealed stricture of pylorus in three patients and antral stricture in one case. Oesophagus was normal in all the cases. Endoscopic biopsy showed evidence of fibrosis and inflammation. After correction of dehydration, the patients were operated.
Laparotomy revealed complete obstruction of pylorus in three patients and antrum in one patient. One patient had antral stricture where we could pass only 10 size Ryle's tube. Posterior gastrojejunostomy was performed in the relatively healthier upper part of the stomach. Postoperative period was uneventful in all four cases. There was rapid recovery and steady gain in body weight in all four patients. Mean duration of follow-up was 20.5 months (range, 4-42 months). Follow-up upper gastrointestinal endoscopy was normal in all the cases.
| Discussion | | |
Easy availability of cheap toilet cleaner makes hydrochloric acid the most frequent cause of corrosive injury in India [3] The tendency of acids " to lick the esophagus and bite the pyloric antrum " is well known. Viscosity and specific gravity of corrosive acids are lower than that of liquid alkalis, hence acids are associated with rapid transit through the esophagus and the damage primarily occurs in the antrum and pyloric region of the stomach. [4] Antral spasm also causes pooling of the corrosive and more damage to the antrum. Another reason for greater susceptibility of stomach is its columnar epithelium whereas esophagus has a more resilient squamous epithelium. [5] The degree of mucosal injury depends on the nature of the agent, the amount and concentration ingested, the amount of food in the stomach at the time of ingestion and the mode of ingestion.
Vomiting, rapid loss of body weight, and decreased oral intake remain the most notable features after acid burns in children. [6]
Timing of surgery is controversial, but early surgical intervention remains the treatment of choice. [2],[7] Feeding jejunostomy and endoscopic balloon dilatation of stricture, [8] gastrojejunostomy with or without vagotomy, [9] pyloroplasty, [6] or antrectomy with Bilroth I anastomosis [10] are the various options available to us. Each procedure has got its merits and demerits. Partial obstruction with moderate mucosal injury usually responds to pyloroplasty. [6] Gastric resection is a major surgery in nutritionally depleted patients and has its associated morbidities. Poor nutritional status and extensive perigastric adhesions are indications of gastrojejunostomy in our patients. Diminution of acid and pepsin production due to damage of glandular elements would weigh against the addition of vagotomy in addition to the drainage procedure. [11] Early surgical intervention resulted in a satisfactory recovery in all four cases with a mean weight gain of 95% (range,50% to 220%) at the last follow-up. There were no symptoms of vomiting or postprandial fullness. Follow-up upper gastrointestinal endoscopy did not reveal any abnormality after 1 year of surgery.
There is a great need for adult education and for legislation to ensure correct labeling, safe packaging in child proof containers and to restrict the strength of caustic agents. Early surgical intervention, individualized according to the site and extent of damage gives excellent result. Gastrojejunostomy is a very safe operation with minimum morbidity and excellent long-term outcome.
| References | | |
| 1. | Ozukutan BH, Ceylan H, Ertaskim I, Yapici S. Pediatric gastric outlet obstruction following corrosive ingestion. Pediatr Surg Int 2010;26:615-8.  |
| 2. | Ciftci AO, Senocak ME, Büyükpamukηu N, Hiçsφnmez A. Gastric outlet obstruction due to corrosive ingestion: Incidence and outcome. Pediatr Surg Int 1999;15:88-91. |
| 3. | Agarwal S, Sikora SS, Kumar A, Saxena R, Kapoor VK. Surgical management of corrosive strictures of stomach . Indian J Gastroenterol 2004;23:178-80. [PUBMED] |
| 4. | Gray HK, Holmes CL. Pyloric stenosis caused by corrosive substance: Report of a case. Surg Clin North Am 1948;28:1041-56. [PUBMED] |
| 5. | Maggi AL, Meeroff M. Stenosis of the stomach caused by corrosive gastritis. Gastroenterology 1953;24:573-8. [PUBMED] |
| 6. | Sharma S, Debnath PR, Agrawal LD, Gupta V. Gastric outlet obstruction without oesophageal involvement: A late sequelae of acid ingestion in children. J Indian Assoc Pediatr Surg 2007;12:47-9.  |
| 7. | Hwang TL, Chen MF. Surgical treatment of gastric outlet obstruction after corrosive injury - can early definitive operation be used instead of staged operation? Int Surg 1996;81:119-21. [PUBMED] |
| 8. | Solt J, Bajor J, Szabo M, Horvath OP. Long-term results of balloon catheter dilation for benign gastric outlet stenosis. Endoscopy 2003;35:490-5. |
| 9. | Ozcana C, Erquna O, Sena T, Mutafa O. Gastric outlet obstruction secondary to acid ingestion in children. J Pediatric Surg 2004;39:1651-3. |
| 10. | Tekant G, Eroglu E, Erdogan E, Yesidag E, Emir H, Buyukunal C, et al. Corrosive injury induces gastric outlet obstruction: A changing spectrum of agents and treatment. J Pediatr Surg 2001;36:1004-7. |
| 11. | Collure DW. Pyloric obstruction following the ingestion of corrosive acid. Ceylon Med J 1989;34:135-7. [PUBMED] |
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