| ORIGINAL ARTICLE |
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| Year : 2012 | Volume
: 17
| Issue : 4 | Page : 153-156 |
Unsuspected invasive neonatal gastrointestinal mucormycosis: A clinicopathological study of six cases from a tertiary care hospital
Sushma Patra1, Mukul Vij1, Dinesh K Chirla2, Narendar Kumar3, Subash C Samal4
1 Department of Pathology, Global Hospitals and Health City, Chennai, Tamil Nadu, India
2 Department of Paediatric Gastroenterology, Rainbow Hospitals, Hyderabad, Andhra Pradesh, India
3 Department of Paediatric Surgical Gastroenterology, Rainbow Hospitals, Hyderabad, Andhra Pradesh, India
4 Department of Gastroenterology, Global Hospitals, Hyderabad, Andhra Pradesh, India
Correspondence Address:
Sushma Patra
Senior Consultant, Pathologist and HOD, Department of Pathology, Global Hospitals and Health City, Chennai, Tamil Nadu - 600100
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0971-9261.102329
Aim: To analyse the clinicopathological features of neonatal mucormycosis Materials and Methods: Retrospective analysis of cases of neonatal gastrointestinal mucormycosis. Results : There were six neonates with male: female ratio of 1:1. Except one all were preterm babies. The clinical presentation was abdominal distension in the majority. All were clinically diagnosed as either NEC or toxic megacolon with perforation. Neonatal gastrointestinal mucormycosis was not suspected clinically in any. All the children were explored immediately. Biopsy revealed transmural hemorrhagic necrosis/infarction of the intestinal wall with fungal hyphae. Conclusions: The physicians should have a high index of suspicion for gastrointestinal tract mucormycosis in neonates with metabolic disturbances who present with abdominal distension and pneumoperitoneum. Early diagnosis and aggressive medical and surgical treatment may improve the outcome of neonates with this potentially lethal invasive disease.
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