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| Year : 2020 | Volume
: 25
| Issue : 3 | Page : 187 |
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Congenital cervical mass in a neonate with secondary scalp swelling
Arti Khatri1, Nidhi Mahajan1, Chabbi Ranu Gupta2, Ekta Narang3
1 Department of Pathology, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi, India
2 Department of Pediatric Surgery, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi, India
3 Department of Otolaryngology, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi, India
| Date of Submission | 18-Oct-2019 |
| Date of Decision | 14-Dec-2019 |
| Date of Acceptance | 11-Jan-2020 |
| Date of Web Publication | 11-Apr-2020 |
Correspondence Address:
Dr. Nidhi Mahajan
Room No. 404, 4th Floor, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi - 110 031
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jiaps.JIAPS_185_19
How to cite this article:
Khatri A, Mahajan N, Gupta CR, Narang E. Congenital cervical mass in a neonate with secondary scalp swelling. J Indian Assoc Pediatr Surg 2020;25:187 |
How to cite this URL:
Khatri A, Mahajan N, Gupta CR, Narang E. Congenital cervical mass in a neonate with secondary scalp swelling. J Indian Assoc Pediatr Surg [serial online] 2020 [cited 2022 Jan 25];25:187. Available from: https://www.jiaps.com/text.asp?2020/25/3/187/282149 |
A rare entity, congenital cervical neuroblastoma (NB) in a 3–week-old male neonate presenting as a large neck mass is discussed [Figure 1]a and [Figure 1]b. Contrast-enhanced computed tomography [Figure 1]c, fine-needle aspiration cytology, and tissue biopsy lead to a definitive diagnosis [Figure 2]. The patient received two cycles of chemotherapy (adriamycin and cyclophosphamide), however succumbed to death due to sepsis. Congenital NB has a good prognosis and may show spontaneous regression despite metastasis.[1],[2] The indexed case is unique in highlighting the rare site, metastasis at presentation, and associated poor outcome. Prenatal diagnosis of these entities ensures timely management and improved survival. | Figure 1: (a) Clinical picture of a huge left cervical mass, (b) scalp swelling, (c) contrast.enhanced computed tomography shows a large heterogeneous mass with central necrosis
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 | Figure 2: (a) Fine-needle aspiration cytology smears are cellular with sheets of large, round cells with focal rosette formation (Giemsa, ×40), (b) focal presence of neuropil amidst the large cells (Giemsa, ×400), (c) tumor cells show strong immunopositivity for synaptophysin (immunocytochemistry, 3,3'-diaminobenzidine as chromogen, ×100), (d) biopsy shows features of differentiating neuroblastoma (H and E, ×400)
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Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
 References | |  |
| 1. | Lonergan GJ, Schwab CM, Suarez ES, Carlson CL. Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: Radiologic-pathologic correlation. Radiographics 2002;22:911-34.  |
| 2. | Gorincour G, Dugougeat-Pilleul F, Bouvier R, Lorthois-Ninou S, Devonec S, Gaucherand P, et al. Prenatal presentation of cervical congenital neuroblastoma. Prenat Diagn 2003;23:690-3. |
[Figure 1], [Figure 2]
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