Home | About Us | Current Issue | Ahead of print | Archives | Search | Instructions | Subscription | Feedback | Editorial Board | e-Alerts | Login 
Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
 Users Online:6180 
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size
 CASE REPORT
Year : 2022  |  Volume : 27  |  Issue : 5  |  Page : 648-651

Doxorubicin extravasation from a port-a-cath into pleural space in a young girl: A case report and review of literature


1 Department of Pediatric Hematology and Oncology, KMC Hospital Mangalore, India
2 Department Surgery, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India
3 Department of Pediatrics, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India
4 Department of Paediatrics, Division of Paediatric Haematology and Oncology, Kasturba Medical College, Mangalore 575 001, Manipal Academy of Higher Education, Manipal, Karnataka, India

Correspondence Address:
Harsha Prasada Lashkari
Department of Paediatrics, Division of Paediatric Haematology and Oncology, Kasturba Medical College, Mangalore 575 001, Manipal Academy of Higher Education, Manipal Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jiaps.jiaps_253_21

Rights and Permissions

Extravasation of chemotherapeutic agents from a peripheral cannula is a known problem, and to prevent that, oncology units use central vein access with indwelling catheters such as port-a-cath or Hickman catheter. The intrapleural extravasation of chemotherapeutic agents is a rare event. We describe a 9-year-old girl with newly diagnosed Ewing's sarcoma of the left upper humerus receiving neoadjuvant chemotherapy through a newly inserted port-a-cath device. The patient developed tachypnea and right-sided chest pain on day 2 of chemotherapy. The radiological investigations confirmed the extravasation of doxorubicin into the pleural space. The surgical washout with chest-drain insertion was done, and we continued flushing with normal saline until the drain fluid became clear. She has completed neoadjuvant therapy. This case report shines light into scenarios where extravasation of anthracycline into the pleural cavity or thorax can be managed conservatively and in settings where dexrazoxane is unavailable without causing much delay in restarting the chemotherapy.






[FULL TEXT] [PDF]*


        
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed163    
    Printed10    
    Emailed0    
    PDF Downloaded13    
    Comments [Add]    

Recommend this journal

 


Contact us | Sitemap | Advertise | What's New | Copyright and Disclaimer | Privacy Notice

  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

Online since 1st May '05